How to Choose Acetonitrile for HPLC Solvents
To choose Acetonitrile for HPLC, select a solvent grade that is specifically designed for chromatographic analysis. Key factors include high purity, low UV absorbance, low residue, consistent lot-to-lot quality, suitable water content, and reliable documentation such as specification, SDS, or COA. For routine HPLC analysis, HPLC grade Acetonitrile is commonly used, while more sensitive techniques such as LC-MS may require LC-MS grade solvent.